We believe this initiative will ultimately lead to new understanding of the underlying causes of lupus along with new therapies for this disease and ultimately an improved quality of life for people living with lupus. For us it is all about the patient!
Lupus is complex and is arguably the most clinically diverse of all autoimmune diseases. Because of this, the scope of the Accelerating Medicines Partnership (AMP) is tailor made for a collaborative effort among the NIH, industry, academic medical research centers and non profit organization.
It's often said that baseball players have to generate 4 hits out of every 10 at-bats to be considered a Hall of Fame-caliber player. Meteorologists are criticized for inaccurate forecasts more often than not. But think about the drug development business: only one in every 5,000 to 10,000 compounds in drug discovery will make it through regulatory approval and even treatments that reach clinical trials only have a 16% chance of approval. (Source: Tufts Center for the Study of Drug Development.
Alzheimer’s disease in the United States is the sixth leading cause of death with more than five million Americans currently struggling with it on a daily basis. Alzheimer’s also represents an area of treatment which has largely failed to materialize.
Autoimmune diseases affect 50 million Americans and are a leading cause of death and disability — yet we have no cure. Historically, the first goal of treatment is to reduce inflammation focusing on making quality of life as good as possible. However, more needs to be done on greater research options for all autoimmune disease-related patients.