Douglas Lowy, MD
National Cancer Institute
Dr. Lowy received his MD from New York University School of Medicine in 1968. Between 1970 and 1973, he was a research associate in the Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, NIH. He trained in internal medicine at Stanford University and dermatology at Yale University, and started his laboratory at the NCI in 1975. Dr. Lowy previously served as the Deputy Director of the Center for Cancer Research from 1996 to 2011, and as Chief of NCI’s Laboratory of Cellular Oncology since 1983. Dr. Lowy is a member of the National Academy of Sciences (NAS) and also a member of the Institute of Medicine of the NAS. He and his long-term collaborator, John T. Schiller, PhD, have received numerous honors, including the 2011 Albert B. Sabin Gold Medal Award and the Federal Employee of the Year Service to America Medal by the Partnership for Public Service.
Dr. Lowy’s laboratory at the NCI Center for Cancer focuses on the molecular biology of tumor viruses and growth regulation.
John Schiller, PhD
Deputy Laboratory Chief / Head, Neoplastic Disease Section
National Cancer Institute
Dr. Schiller graduated from the University of Wisconsin-Madison with a BS in molecular biology in 1975. In 1982, he received a PhD from the Department of Microbiology of the University of Washington in Seattle, and then joined the Laboratory of Cellular Oncology as a National Research Service Award postdoctoral fellow in 1983. Dr. Schiller became a senior staff fellow in the Laboratory of Cellular Oncology in 1986 and a senior investigator in 1992. In 1998, he became chief of the Neoplastic Disease Section of the lab. Along with colleague Douglas Lowy, he has been honored with the Albert B. Sabin Gold Medal Award and the Federal Employee of the Year Service to America Medal by the Partnership for Public Service
Dr. Schiller’s research has focused on the basic biology and vaccine development for human papillomavirus.
Dr. Douglas R. Lowy and Dr. John T. Schiller are receiving the 2013 Research & Hope Award for Academic or Public Research for the integral role they have played in the development of the human papillomavirus vaccine against cervical cancer, performing fundamental research regarding the nature of the virus, animal studies, and a Phase I trial in humans. Their research directly led to the first HPV vaccine, approved by the FDA in 2006, which has the potential to drastically reduce the incidence of cervical cancer in women.
Today, in addition to their ongoing study of papillomavirus – including the potential use of PV pseudovirus as gene transfer vehicles – Drs. Lowy and Schiller are working with colleagues at the World Health Organization and other organizations to find ways to distribute HPV vaccines to those in need.